Sentence examples for binding and gene expression from inspiring English sources
Importantly, the boxplot representation revealed a similar correlation as Pol II between Msl1 binding and gene expression, indicating that the stronger the gene is expressed the higher Msl1 and Pol II are enriched at the binding sites.
Integration of genomic features with chromatin interaction data provided evidence for hundreds of connected cis-regulatory domains associated with differences in transcription factor binding and gene expression.
We used an integrated transcriptomic and epigenomic approach to analyze chromatin accessibility, histone modifications, transcription-factor binding, and gene expression in IFN-γ-primed human macrophages.
Clearly, no single approach captures a clear and complete view of transcriptional systems suggesting a combination of approaches is likely needed to more fully understand the relationship of transcription factor DNA binding and gene expression.
The definition of transcriptional networks through measurements of changes in gene expression profiles and mapping of transcription factor binding sites is limited by the moderate overlap between binding and gene expression changes and the inability to directly measure global nuclear transcription (coined "transactome").
Differential footprints reveal links between TF binding and gene expression.
This cross-platform resource provides many opportunities for integrating TF-binding and gene expression data to explore molecular mechanisms underlying changes in cell fate.
Stratification of binding data also helped identify enriched DNA motifs and link them to both TF-binding and gene expression information.
An independent approach to associate TF binding events with gene expression outputs is to map mathematically between the binding events and gene expression patterns collected over many conditions.
The interplay among DNA methylation sites, genetic variation, protein binding sites, and gene expression is a very active field of investigation.
Through the relative analysis of recognized transcription factor binding status and gene expression profiling, a model for each transcription factor can be fixed with concrete parameter values.
