Sentence examples for binding and effector interaction from inspiring English sources

Galpha subunits bound to guanine diphosphate (Galpha-GDP) inhibit signal transduction through Gbetagamma subunits, suggesting a common interface on Gbetagamma subunits for Galpha binding and effector interaction.

Gα subunits bound to guanine diphosphate (Gα-GDP) inhibit signal transduction through Gβγ subunits, suggesting a common interface on Gβγ subunits for Gα binding and effector interaction.

Although the VEGF receptors share considerable overlap in ligand binding, downstream effector interaction and biologic function, predominant actions have been identified.

A small example system that is discussed below contains the following processes: ligand binding, binding site phosphorylation and effector binding.

Our results demonstrate that removal of fucosylated antibody ingredients from antibody therapeutics elicits high ADCC in human blood by two mechanisms: namely, by evading the inhibitory effects both of plasma IgG on FcγRIIIa binding (effector side interaction) and of fucosylated antibodies on antigen binding (target side interaction).

Although previous work by several groups have clearly demonstrated the importance of the A-domain of proteins of the XylR/DmpR subfamily of transcription activators in effector recognition, the actual effector 'binding' region and the type of effector interaction have largely remained elusive.

N-terminal sequences of T3SS effectors contain secretion signals and often mediate chaperone effector interactions (Harrington et al., 2003).

The sensitivity, duration and (ir)reversibility of the switch is controlled by the kinetics of ligand binding, the ATPase activity and eventual downstream effector interactions.

A typical case is the interaction of the processes of binding site phosphorylation and effector binding.

However, if there are graded interactions that connect the binding site phosphorylation and effector binding processes indirectly, these two processes have to be described in the same layer.

However, safety liabilities associated with peripheral receptor binding and Fc effector function have been reported.