Sentence examples for binding and effectively from inspiring English sources

This indicates that the CT domain specifically competes with microtubules for MCAK binding and effectively reduces the affinity of MCAK for microtubules.

An incompatibility arises whenever the fitness of the hybrid is − ∞ [ h 12 > r   * or h 21 > r   * ], i.e., when a hybrid TF TFBS specific binding is weak compared to the nonspecific mode of binding and effectively can no longer recognize its target site.

Mithramycin has affinity for the GGGCGG binding sequence, and effectively blocks the binding of Sp1 [24].

The mutant NBS1 protein retains the binding ability and effectively suppresses the expression level of the MRN in infected cells.

In contrast, varenicline competitively blocks nicotine from the binding site and effectively reduces nicotine-induced DA elevation in vivo by 40 55% (Rollema et al., 2007).

When bound to their target sites, LexA dimers physically hinder RNA-polymerase binding and thereby effectively repress gene expression.

A new tetradentate N,N′,O,O′-ligands possessing fixed preorganised conformation geometry for metal ion binding are proposed and effectively synthesised.

Our findings suggest that circulating sialoadhesin-expressing monocytes are capable of binding HIV-1 and effectively delivering virus to target cells thereby enhancing the distribution of HIV-1.

In other words, nutlin competitively displaces p53 from the binding on MDM2 and effectively causes the stabilization of p53.

Antisera raised against gp64 peptides, which span the residues of the fusion patch, prevent virus binding to cells and effectively neutralize virus infectivity [ 15] and similar data linking the sequences identified with fusion with direct cell binding has been presented for Herpes gB [ 16].

Just as remarkably and in contrast to expectations based on the steric constraints of the tubulin binding site surrounding the vinblastine C20′ center depicted in the X-ray cocrystal structure of a tubulin bound complex, large C20′ urea derivatives are accommodated (e.g., biphenyl), exhibiting potent functional activity in cell-based proliferation assays and effectively binding tubulin.