Sentence examples for binding and displacement of from inspiring English sources

Among the tested molecules, tetracyclines showed a peculiar behavior by giving very high induction in a fashion seemingly more related to a general stress condition of the culture than to the direct binding and displacement of QacR from its operator.

This also has implications for binding and displacement of protein ligands other than RAP.

Binding of Ca2+ to Lig A9 and Lig A10 proceeds with a negative enthalpy change (ΔH) which is due to ligand-binding and displacement of water of hydration at binding interface.

These operate variously through altered cofactor binding, degradation and displacement of NF-κB from DNA.

During signaling events causing a Ca2+ rise, binding of Ca2+ ions to these sites results in sequential conformational changes (partially active form), dissociation of the CaM-binding region, binding of CaM, and displacement of the autoinhibitory inhibitory peptide from the active site (fully active form).

While chromatin accessibility is a main determinant of TF binding (Biggin, 2011), chromatin structure and indirect cooperativity (increase in the occupancy of a TF caused by other proteins' binding and partial displacement of the nucleosome from the DNA) (Polach and Widom, 1996) do not entirely explain the extensive overlap of Hoxa2 and TALE.

Increased MMF intolerance in advanced renal failure may be a direct toxic effect of AcMPAG or indirectly by an increase in free MPA, due to altered protein binding and the displacement of MPA from protein by MPAG [ 35, 43, 44].

The modulations include the distortion of the glycine-rich loop, blockage of the ATP binding site, and activation segment conformation and displacement of the αC-helix.

We also report the structure of a (Cse4:heterotetramerramer; comparison with the structure of the Scm3 Cse4:H4 complex shows that tetramer formation and DNA binding require displacement of Scm3 from the nucleosome core.

These include formation of a partially closed Prp8 conformation that creates, together with Dim1, a 5′ splice site (ss) binding pocket, displacement of Sad1, and rearrangement of Brr2 such that it contacts its U4/U6 substrate and is poised for the subsequent spliceosome activation step.

This phosphorylation brings about changes either in chromatin architecture or the binding or displacement of histone "reader" proteins from chromatin.