Sentence examples for binding and dimerization domains from inspiring English sources

Coupled with our observation that TraR proteins from the two major clades cannot efficiently cross-dimerize, our results suggest that both DNA binding and dimerization domains of TraR proteins are structurally and functionally conserved within, but not between the clades.

E2F6 is unique in that it retains the conserved E2F DNA binding and dimerization domains, but lacks the C-terminal transactivation and pocket protein binding domains characteristic of other members [31] [33].

Several substitutions affecting H. pylori Fur's ∼10 residue N terminal arm, which has no counterpart in prototype (E. coli-type) Fur proteins, increased Mtz resistance, as did mutations affecting the region between DNA binding and dimerization domains.

The E2F family regulates overlapping sets of target genes, and all contain related DNA binding and dimerization domains.

However, both isoforms contain DNA binding and dimerization domains, indicating separate functions of the isoforms, and not a simple dominant negative function of the short isoform.

In particular, comparison of the DNA binding and dimerization domains of SlmA with QacR yielded a root mean squared deviation (RMSD) of 1.9 Å and 3.9 Å, respectively.

One large superfamily of TFs characterized by the basic-helix-loop-helix (bHLH) DNA binding and dimerization domain is critical for development in almost all eukaryotes (Jones 2004).

Although DIPA contains a basic region-leucine zipper DNA binding and dimerization domain, which has similarities to FRA family members [ 47], DIPA has never been reported to interact with the AP-1 complex, EGR4 or FHL2.

This derivative retains LR1, nuclear localization sequence (NLS), and the DNA-binding and dimerization domains.

TrlR has functional ligand-binding and dimerization domains, but lacks the C-terminal DNA-binding domain (Oger et al. 1998; Zhu and Winans 1998; Chai et al. 2001).

Given the strong conservation of motifs between fungi and animals in the DNA-binding and dimerization domains, we hypothesize that the molecular function of these fungal proteins will be very similar to their animal homologs, i.e., they are transcription factors that will bind DNA targets, most likely as dimers (like GRH).