Sentence examples for binding and degradation of from inspiring English sources

In high-risk HPVs (i.e., those that are more likely to cause lesions that may develop into cancer [ www.cancer.gov/cancertopics/factsheet/Risk/HPV]), E6 and E7 deregulate cell cycle control by E6 binding and degradation of p53, and E7 binds and inhibits the function of the retinoblastoma protein (Rb) (3 ).

Taken together, these data suggest that phosphorylation of β1 at Ser prevents its binding and degradation of p27Kip1, whereas dephosphorylation of β1 at Ser increases its ability to bind and degrade p27Kip1, thus promoting cell proliferation.

Our data demonstrate that phosphorylation of β1 at Ser prevents its direct binding and degradation of p27Kip1 while dephosphorylation of β1 at Ser increases its ability to bind and degrade p27Kip1.

The molecular mechanism involves the binding and degradation of specific host microRNA.

This results from the binding and degradation of a host miRNA, miR-27, to a viral snRNP.

The molecular scale comprises secretion, diffusion, binding and degradation of cytokines (tumor necrosis factor-α, interleukin-10) and chemokines (CCL-2, CCL-5, CXCL-9).

In Brown and Goldstein (1979), the dynamics of binding, internalization, and degradation of LDL by LDL-R mediated uptake were studied using radio labeled LDL (I-LDL).

These results demonstrate that BAG2 interacts with mutp53, and inhibits MDM2 binding to and degradation of mutp53, which leads to the mutp53 accumulation in cells.

The kinase-mediated phosphorylation of proteins, lipids, and carbohydrates controls the activation/deactivation, cellular localization, binding affinity, and degradation of the substrate molecules.

Transformation of the BEAS-2B immortalized human epithelial cell line by JSRV appears to require RON activation, as a result of JSRV Env binding to and degradation of the virus receptor Hyal2, which appeared to negatively regulate RON activity.

Since k i is a combination of promoter strength, ribosome binding site and degradation of the transcript, there are some variations or uncertainties on the parameter value k i.