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Intracellular signaling pathways are triggered following antibody binding and crosslinking of cell surface molecules [25].
During synthesis of the bead-based immunomatrix it was critically important to use a neutral wash buffer after binding and crosslinking of the antibody to the protein A beads.
This mutation abolishes the binding and crosslinking of [H]azocholesterol to NPC1 (Ohgami et al., 2004).
Mast cells assist in these responses in part by undergoing the process of degranulation, in which preformed mediators such as histamine, serine proteases, and proteoglycans are released after stimulation by antigen binding and crosslinking of IgE bound to FcεRI receptors at the cell surface.
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In support of this idea, re-expression of full-length FLNa rescues the defect in initiation of migration in FLNabKD cells, but the phenotype is not rescued by the FLNaΔ19 21 mutant, which should still be capable of binding and crosslinking F-actin [33].
In order to test the binding and potential crosslinking of recombinant DR1 molecules by SEA in solution, we performed a "gentle SDS" PAGE assay to probe the conformational stability of DR1 complexes [22], [28].
It is certainly likely that a similar set of clustering events, in this case on the DR1 expressing B cell membrane, could be initiated by SEA binding and crosslinking DR1 molecules.
Constant fibrous capsule layers and number of inflammatory cells were observed regardless of the incorporation of cell-binding peptide and crosslinking density of OPF hydrogels with PEG block length of number average molecular weight 930±90.
IP-DNA was purified by A/G plus-agarose protein binding and crosslinks were reversed at 65°C overnight.
Current review highlights emerging strategies for the design of DNA-binding peptides and crosslinking techniques capable of interference at the DNA protein interface with emphasis on bottom-up organic synthesis.
It is possible that phosphorylation induces conformational changes that are more permissive for curcumin binding and/or crosslinking of the protein and thus curcumin is more effective in these cells.
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binding and insertion of
binding and internalization of
binding and retention of
binding and reduction of
binding and dissociation of
binding and phosphorylation of
binding and internalisation of
binding and regulation of
binding and stability of
binding and activation of
binding and function of
binding and elimination of
binding and positioning of
binding and activity of
binding and removal of
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