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The variability of reported Ki may partially be explained by microsomal binding and choice of inhibition model.
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Assuming the minimal involvement of lipid acyl chain region into the protein site recognition during the initial stage of CT binding, this choice of the ligand mimicking PS seems to be justified.
Considering that the majority of mixture studies have been based on end points relatively close to the steps following hormone-receptor binding and activation, the choice of dose addition appears to be well-founded.
The cost is $20 a square foot; cotton binding in a choice of 40 colors is an extra $10 a running foot.
Even in the presumably inert cullin scaffolding proteins, it was observed that different loop lengths in the amino-terminal domains confer different dynamical behavior, which allosterically affects the binding site, and thus the choice of partner.
In other words, we hypothesized that non-central remodeling accompanies the binding of one or more GR cofactors and that choice of cofactor is impacted by DNA sequence.
(c) Multiple binding and elution of QMC-beads.
Figure 7: Ion binding and modulation of prokaryotic TRIC.
These studies demonstrate how cavity complementation and judicious choice of site can be used to produce a protein template with an unusual ligand-binding specificity.
Iron binding and releasing properties of rhLF.
And the choice of vocabulary insinuates preconceptions.
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