Sentence examples for binding and cellular activation from inspiring English sources
To determine whether GAG binding plays an important role in receptor binding and cellular activation by MIP-1 beta, the activities of wild-type MIP-1 beta and R46-substituted MIP-1 beta were compared in assays of T lymphocyte chemotaxis.
This could facilitate the analysis of effects of specific IgG preparations added to the cells, regarding receptor binding and cellular activation, without the interference of pre-bound IgG.
We demonstrate for the first time that nanoparticle binding and cellular activation are sensitive to membrane spatial organization, which is particularly important during T cell activation.
Antibody binding to endothelium and subsequent cellular activation involving complement-dependent and -independent pathways leads to the recruitment of natural killer (NK) cells, polymorphonuclear neutrophils and macrophages, which contribute to capillaritis and eventual tissue injury 15– 15.
AIF1, also known as Iba1, is a 17 kDa protein and calcium-binding molecule involved in cellular activation and cell cycle progression [63], [64].
These molecules are transmembrane receptors that, on binding to extracellular ligands, trigger cellular activation and proliferation.
RAGE binding with various ligands sustained cellular activation in inflammation in acute spinal cord injury27.
As a member of the immunoglobulin receptor superfamily, FcεRI consists of a ligand-binding immunoglobulin domain-containing protein (α-chain) which binds the Fc-part of IgE and signaling subunits that regulate cellular activation (β- and γ-chains) [2].
This change also disrupts DNA binding and transcriptional activation, with little effect on cellular localization.
This soluble form of the receptor has the same ligand binding specificity and therefore competes with cell-bound RAGE for ligand binding, therefore functioning as a 'decoy' abrogating cellular activation, since the cell surface receptor remains unoccupied.
Galectin-3 is a β-galactoside-binding protein that has been shown to regulate pathophysiological processes, including cellular activation, differentiation and apoptosis.
