Sentence examples for binding and cell uptake from inspiring English sources

On the basis of our previous study, Trp improves siRNA binding and cell uptake, while His facilitates endosomal escape due to the pH-responsive nature of the imidazole ring.

In vitro studies including radioreceptor binding assays in the rat brain membrane and cell uptake studies in the A375 cell line were performed.

Moreover, cell membrane binding and dendrimers cell uptake together with fluorophore-conjugated oligonucleotides was evaluated using TIRF microscopy showing dendrimers different behavior with the plasma membrane.

This study was designed to investigate the effect of fatty acyl chain length on physicochemical properties, pDNA binding affinity, cell uptake, and in vitro transfection efficiency of N-acyl chitosan (NAC).

The previous nanocarrier was functionalized with a 5 kDa proteolytically removable PEG corona; cleavage of this layer shifted the nanoparticle's zeta potential from +6 to +15 mV, resulting in increased cell binding, cell uptake, and gene-silencing activity.

We further assessed the bead binding and uptake per cell amongst each protein condition for each of the four bead sizes.

The analysis of differences in cell binding and kidney uptake was performed using Student's t-test.

For fluorescent transferrin binding and uptake assays, cells were preincubated in DMEM, 25 mM Hepes, 0.5% BSA at 37°C for 1 hr to remove bound transferrin.

The DOTA-knottin 3-4A peptide was radiolabeled with 64Cu, and tumor cell binding and uptake were measured using U87MG glioblastoma cells (Figure S3).

This enhanced cytotoxicity of MBDC in MCF-7 breast cancer and HT-29 colon cancer cell lines may be due to their efficient targeted binding and eventual uptake by the cells.

In addition to their promise as vehicles for the delivery of molecular cargoes, such as cytotoxic agents, selectively to tumor cells the saccharides characterized in the present study may find utility in the characterization of the cell surface receptors responsible for tumor cell binding and uptake of BLM saccharides.