Sentence examples for binding and cell surface from inspiring English sources
The effects of these mutations on IGF binding and cell surface association have been characterized in vitro by others [6], [22], [23].
However, P. gingivalis cannot synthesize this iron porphyrin and thus acquisition from exogenous sources, coupled with its binding and cell surface storage, is essential for the growth and survival of this bacterium.
Particularly interesting mutants are MT1-I49N, whish is devoid of any melatonin binding and cell surface expression, and MT1-G166E MT1-I212T212T, which showed severely impaired cell surface expression.
The model is based on mass-action kinetics describing binding and cell surface trafficking interactions for VEGF with VEGFR1, VEGFR2, NP-1, and ECM sites and builds on previous work from Popel and co-workers[ 15- 20].
RAMP1 and CLR dimerization is required for both ligand binding and cell surface expression [19] and CLR is also known to form an adrenomedullin receptor when it forms a heterodimer with either RAMP2 or RAMP3 [19].
The binding properties were analyzed in competitive binding, internalization, and cell surface retention experiments.
Treated cells were also subjected to rGEP binding assay and cell surface GEP detection.
We previously reported that the R450H mutation led the receptor function to the moderate impairment of cAMP response to TSH, TSH binding activity, and cell surface expression [ 4].
The third important point for discussion is the fact that the inverse correlation between peptide binding repertoire and cell surface expression level also correlates with resistance and susceptibility to certain infectious pathogens.
Since endogenous agonist binding properties and cell surface receptor expression levels are normal for this Val103Ile polymorphism, it had been difficult to link the Ile103 allele with a potential molecular effect.
The GO analyses showed that the most common molecular function was binding activity, which included ion binding, protein binding, carbohydrate binding, pattern binding, cell surface binding, and lipid binding.
