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Zeevi, A. et al. Persistent strong anti-HLA antibody at high titer is complement binding and associated with increased risk of antibody-mediated rejection in heart transplant recipients.
These data indicate that the Hp fractions examined are equivalent to one another with respect to Hb binding and associated stability and redox properties and that this result should be taken into account in the design of phenotype-specific Hp therapeutics aimed at countering Hb-mediated vascular disease.
And this receptor binding and associated downstream signalling activity causes the psychotropic and therapeutic effects that come along with smoking weed.
In cancer, mutation of p53 disrupts protein conformation with consequent loss of DNA binding and associated tumour-suppressor function.
These results indicate that Arg-120 may be an important residue for Pi binding and associated conformational changes.
Residue Arg-120 was found to play an important role in Pi binding and associated conformational changes.
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The published ChIP datasets also identified large numbers of binding intervals and associated genes (BDTNP = 6452 binding intervals and modENCODE = 3520 binding intervals at FDR1%, mapping to approximately 6500 and 3500 genes, respectively).
A variant predicted to affect a splicing regulatory protein-binding site was consistent with validation experiments explicitly assessing binding affinity and associated splicing alterations.
Further, crXNA and tracrXNA provide novel tools for interrogating Cas9 activity and structural requirements through careful manipulation of binding affinities and associated chemical moieties.
While three tyrosine phosphorylation sites have been characterized biochemically, the binding capabilities and associated functions of several other potential phosphotyrosine motifs remain unclear.
The downstream targets of insect dsx are not well elucidated, however 58 optimal binding sites and associated nearest genes have been identified for D. melanogaster Dmdsx [ 15].
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