Sentence examples for binding and activity of from inspiring English sources

Mice with targeted deletion of p50 (p50−/−) are more sensitive to cigarette smoke induced emphysema, demonstrating enhanced lung inflammation, and enhanced DNA binding and activity of the transcriptionally active p65/p50 dimers in association with alterations in chromatin remodeling (Rajendrasozhan et al., 2010).

Binding of BaP adducts to DNA decreased methylation by reducing binding and activity of DNMTs [ 112, 113].

Using EMSA and overexpression assays, we thus examined the effect of 5ʹUTR methylation on the binding and activity of SP1, SP3, SUB1 and DEAF1, all of which bind to and repress the GDF5 5ʹUTR (Syddall et al. 2013).

The alanine substitution of K203 that directly interacts with RNA cap was expected to severely influence the binding and activity of the cap1 MTase.

Here, we investigate the DNA binding and activity of the bacteriophage T7 primase using a new workflow called high-throughput primase profiling (HTPP).

As expected, the K203A substitution in CMTr1 strongly affects both the binding and activity of the enzyme, whereas R228A does not (Fig. 5), demonstrating that the method is able to discriminate between the residues that interact with substrate and those that do not.

The carboxyl end of p21WAF1/CIP1 mediates the PCNA-binding and activity of DNA polymerase δ (Chen et al, 1995; Luo et al, 1995; Nakanishi et al, 1995; Warbrick et al, 1995).

Ligand binding, expression, and activity of this receptor are important for atopy and asthma.

Zheng, Y., Humphry, M., Maguire, J. J., Bennett, M. R. & Clarke, M. C. Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1alpha, controlling necrosis-induced sterile inflammation.

Phosphorylation can affect binding properties, localization and activity of proteins and receptors [ 4].

The DNA binding specificities and activities of the isoforms also differ.