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Kinetics of binding and accumulation of [125I]SGMIB-MNT by (a) A431 human epidermoid carcinoma cells and (b) D247 MG human glioma cells.
The scavenging effect is a key source of forest soil contamination, and the high amount of natural organic matter in forest soil also provides better conditions for the binding and accumulation of PAHs in soils [8, 29, 39].
Heat shock (HS) treatment of Leishmania parasites leads to intracellular binding and accumulation of the caspase inhibitor fluorescein isothiocyanate-valyl-alanyl-aspartyl-[ O-methyl]-fluoromethylketone (FITC-VAD-FMK).
Interestingly, in maternal Trim28 mutant embryos with hypomethylated ICRs, TRIM28 and ZFP57 binding and accumulation of H3K9me3 was lost and never recovered, even when TRIM28 from the paternal allele was expressed (unpublished observation).
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Treatment of cultured neurons with fibrillar Abeta results in an increase of Tau phosphorylation, leading to a loss of microtubule-binding capacity and accumulation of Tau in the somatodendritic compartment (Busciglio et al. 1995).
Multimodal liposomes endowed with contrast material for complementary imaging technologies, e.g., MRI and optical, can be exploited to gain important preclinical insights into the mechanisms of binding and accumulation at angiogenic vascular endothelium and to corroborate the in vivo findings.
The unbound non-ionized volume of distribution, Vdf, accounts for the effect of protein binding and membrane accumulation of chemicals on the available concentrations (eqs 23 and 24), and on the decrease in the elimination rates (eqs 62 and 63).
Treatment of bMSC with adipogenic factors increased levels of fatty acid-binding protein 2 (AP2) mRNA and accumulation of lipid vacuoles after 18 days of culture.
Consistent with previous work,, we also detected a strong increase in DNMT1 binding and an accumulation of phospho-H2AX at these CpG islands (Fig. 6B), as well as a reduction of cMyc protein (Fig. 6C) and mRNA (not shown).
Mutation of glutamine to glutamic acid on VP1 145 region cooperatively promote viral binding and RNA accumulation of EV71, contributing to viral infectivity in vitro and mouse lethality in vivo[ 35].
Thus, adult muscle tissues are characterized by loss of NF-Y binding, concomitant accumulation of negative and reduction of permissive marks of transcription.
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binding and insertion of
binding and stability of
binding and reduction of
binding and activation of
binding and entry of
binding and regulation of
binding and transactivation of
binding and stimulation of
binding and presentation of
binding and induction of
binding and transport of
binding and function of
binding and interaction of
binding and phosphorylation of
binding and internalization of
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