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Our study is unique in that none of the published studies performed in silico transcription factor binding analysis based on major gene profiles to gain insights into the γ/β globin switching described below.
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In order to obtain the information of the valence of these compounds, we have performed a systematic tight-binding analysis based on ab-initio calculation.
Given the O2-binding curve, the analysis based on Eqs. 1 and 2 yields the pH-dependent P50 and nHill of Hb with and without IHP over the pH range from 6.6 to 7.5 (Fig. 4).
HLA-A24 binding peptides selected by an analysis based on HLA-A24 binding motifs were determined for their binding affinities to HLA-A24 molecules.
The decision by Sato et al. [ 28] to assign putative fish killer cell receptors to group V rather than to group II was based on several considerations, including gene structure, absence of canonical Ca2+/carbohydrate-binding residues, and phylogenetic analysis based on the CTLD alignment.
We pursued an integrated molecular analysis based on methylation binding domain sequencing (MBD-seq), 450K Methylation arrays, whole exome sequencing, and whole genome gene expression arrays in primary head and neck squamous cell carcinoma (HNSCC) tumors and matched uvulopalatopharyngoplasty tissue samples (UPPPs).
In order to evaluate the evolutionary relationship among the rice Dof proteins, we performed a phylogenetic analysis based on their DNA binding domain sequences.
We then applied a novel analysis based on integrating global protein-RNA binding with concurrent changes in RNA stability at specific time points following activation.
To elucidate the binding properties of haem for ANT, we used computational analysis based on the BtAAC1 structure.
Under such cases, detailed chemical exchange analysis based on chemical shift perturbation will assist in locating the binding site accurately.
Interestingly, a recent analysis based on zebrafish VDRα36 demonstrated that VDR also presents an alternative-binding site when co-crystalized with the agonist lithocholic acid.
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