Sentence examples for binding affinity will be from inspiring English sources

The pH-dependent binding affinity will be the subject of a future molecular dynamics study that goes well beyond the scope of the present manuscript.

If a conformation capable of recognizing a specific ligand is only populated a fraction of the time, unless that conformation has a high intrinsic affinity for the ligand, the overall binding affinity will be very weak, as the effective concentration of binding-competent receptor is reduced.

If the pattern of interaction is very different between the input and humanized sequence, it can be expected that the resulting binding mode, and most likely the affinity, will be different.

The result is a list of compounds ranked by a scoring function that estimates the activity on the target (binding affinity, equilibrium constant, binding energy), which will be confirmed experimentally.

The presence of the newly identified AVB-binding epitope will be useful for affinity resin selection for the purification of novel AAV serotypes.

Sometimes quantitative affinity measurements will be made for a subset of binding sites and then predictions of affinities to all sites are extrapolated based on a model [1] [4].

Although we were unable to develop coiled coil peptides with high binding affinities, the present results will be useful for designing novel coiled coil peptides.

Therefore, when the amount of antigen is limited, B cells that have higher receptor-binding affinity to the antigen will be preferentially activated, producing ADA with higher average affinities over time.

Despite these results, the approximate binding affinity calculation will still be useful to assess the docking of complexes when the binding mode is unknown.

In the future, computers will assist drug design efforts not only in predicting the binding mode of a small molecule and its binding affinity, but also how the drug will be absorbed and metabolized in the body as well as its potential toxicity.

Thus, how a sprout experiences the ordering of the isoforms by sensing matrix-bound VEGF may not always be monotonic with respect to the heparin binding affinity of the VEGF isoform; it will be dependent on the distance between the sprout and the VEGF source.