Sentence examples for binding affinity which supports from inspiring English sources

By contrast, the nature of nucleotides at position N3 and N12 can either enhance or reduce the binding affinity, which supports their contribution in determining the binding specificity of various ERFs to target promoters.

However, MrkH116-end loses the c-di-GMP binding affinity, which indicates that the connecting loop between two β-barrels is crucial for c-di-GMP binding.

A recent study showed that phosphorylation of Twist1 affected its dimer affinity for a given partner and modulated the DNA binding affinity, which might control limb development [10].

The occurrence of hydrophobic hydration on the ice binding surface is likely unnecessary for enhancing protein-ice binding affinity which is achieved by a tight H-bonding network.

Our study reveals that IFNAR1 flexibility modulates ligand-binding affinity, which, in turn, regulates biological signaling.

High and low affinity ATP binding sites have been observed for MLH1 and PMS1 in yeast [ 74] which supports the ATP binding and ATPase activity predictions for their human orthologs [ 75].

The number of companies which support the binding deal has also been reduced from 808 to 805.

Coupled with the observation that 5′ and 3′ blockages of the aptamer sequence exhibit similar changes in binding affinity, this too supports the notion that only thermodynamic properties are responsible for the observed modulations in aptamer binding affinity.

In addition, according to the data from the cell protection and SPR assays, both M1 and M2 mutants, which contain the L56A mutation, had a striking increase in protective ability and PA binding affinity, further supporting the important role of position 56 in determining PA-binding affinity.

These findings are confirmed by binding affinity calculations which are in good agreement with experiment.

Importantly, ADP binds with low affinity, which is insufficient to interfere with binding or release of these high affinity inhibitors.