Sentence examples for binding affinity when the from inspiring English sources

The only exception is related to the multiple operator sites, where the second repressor binds an operator site with higher binding affinity when the first site is already occupied by the repressor protein [ 47].

Quantum calculations suggest that the energetic cost for the proximity between the backbone carbonyl and ribose O2′ was only ∼2.2 kcal/mol, similar to the observed loss of binding affinity when the wild-type enzyme binds ribonucleotides.

SEM indicated that the structure of cement paste tends to be more compact with lessened porosity and increased interfaced binding affinity when the added glass powder is relatively fine.

That aspect is the increase in binding affinity when the KCl concentration is increased from 25too 150 mM.

Nevertheless, the standard PWM formulation fails to predict binding affinity when the latter decreases to the point of non-specific binding [ 44].

However, it performed worse when the number of top ranked peaks increased, suggesting that it distorts the binding affinity when the signal turns weaker.

Further deletions showed that the region 415 to 461 of PIASy was critical for association with VHL, although the central region (aa 233 to 415) showed similar binding affinity when compared to the complete loss of binding with the mutant containing only the first 233 residues (aa 1 to 233) (Figure 4A, lane 3, 4).

The stabilised monovalent scFv antibody 4.9M exhibited 45-fold reduced binding affinity when compared with the parental humanised IgG.

The interphase-specific H3 kinase, MSK1 phosphorylates H3Ser10 with the highest binding affinity when Lys9Lys14 are non-acetylated.

This suggests that we should use the calculated binding free energy if possible instead of the approximate binding affinity when designing new Compstatin variants.

Despite having equal thermodynamic binding affinity, when mechanically dissociated by pulling from the N-terminus of Doc, binding mode A was more mechanically stable with an additional energy barrier.