Sentence examples for binding affinity was studied from inspiring English sources

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The cation binding affinity was studied using colorimetric and UV Vis spectral methods for the three receptors.

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In this study, a 3D pharmacophore was generated for a set of LAT1 substrates whose binding affinities were studied using competitive inhibition of the brain uptake of [14C]-l-leucine with an in situ rat brain perfusion method.

The resulting mutant proteins were purified, and their binding affinities were studied by surface plasmon resonance.

In this study, the binding affinity was estimated by using an implicit-solvent model in which the electrostatic contributions were obtained by solving the Poisson equation, and the hydrophobic effects were accounted for by using surface-area-dependent terms.

In this study, we found three aptamers, and binding affinity was determined by fluorescently labeled aptamers.

The strongest binding affinity was to GM3, which has the same saccharide sequences as the 3'-sialyllactose used in this study.

The apparent binding affinity was derived from 3 or more experiments.

HER2 binding affinity was determined in saturation radioligand binding assays using SKBR-3 cells (1.3 × 106 HER2/cell).

The effect of ligand concentration on protein stabilization and its relationship with binding affinity is complex and has been studied theoretically and experimentally.[ 18] It has been concluded that, in general, for 1 1 protein ligand binding and a simple two-state approximation of the unfolding transition, Δ Tm should correlate reasonably with both affinity and ligand concentration.

This study confirms that the tRNAphe binding affinity is greater for TO compared to TBO.

While in vitro binding studies of transcription factors with differential binding affinities could be pursued, it has been well established that computational predictions of binding affinity are highly correlated with experimental measurements [ 56].

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