Sentence examples for binding affinity was observed from inspiring English sources

A significantly high binding affinity was observed for the PKR-inhibitor to the MARK4 variants.

The result showed that biotin-As bound to PML-RARA, similar binding affinity was observed with PML-RARA-L217F and S220G (Fig. 1D and 1E).

A considerable enhance in the binding affinity was observed, when compared with the zwitterionic PC, with a Kd of 0.04 µM.

However, significant improvement of binding affinity was observed with KDED7 truncation (KDED7a) and the various forms of KDED2 (KDED2a, KDED2and and KDED2a-3), as demonstrated in the improved affinities of the truncated versions (Table 2).

Indeed, a similar lack of effect on drug binding affinity was observed when QacR residues E57 and E58 were substituted with glutamine or alanine [21] and even when double glutamate substitutions (E57Q/E58Q) were made (Peters et al., data not shown).

In case of RGPD/HMPR double mutant, an increase in binding affinity was observed compared with the original mutants (Table 2).

Therefore we will consider only cases where a decrease in the binding affinity is observed.

No differences in receptor binding affinity were observed, and all samples demonstrated similar in vitro bioactivity.

All three mutants bound to PG like the wild-type, and no significant differences in the binding affinity were observed.

A larger loss of Zn II) binding affinity is observed when His94 is replaced with Ala (Kd = 270 nM).

Importantly, such experiments revealed the complex nature of TF-DNA interactions, whereby the effects of nucleotide changes on the binding affinity were observed to be context dependent.