Sentence examples for binding affinity was assessed from inspiring English sources
The possible formation of a three-centred hydrogen bond (HB) at the HB donor site H2, as a key interaction for high receptor binding affinity, was assessed by the calculation and comparison of the molecular electrostatic potentials of a series of selected ligands.
The integrin αvβ3/αvβ5 binding affinity was assessed via a cellular competitive displacement assay using I-echistatin (PerkinElmer, Branford, CT) as integrin-specific radioligand.
Then, the TFR-binding affinity was assessed by the same method as described above in section TFR-competition binding affinity assay in Caco-2 cells.
Accordingly, the benzoxazolone moiety was replaced by other heterocyclic scaffolds, the relevant conformational space in the σ1R binding cavity was explored, and the effect on σ1R binding affinity was ultimately assessed.
The apparent binding affinity was derived from 3 or more experiments.
HER2 binding affinity was determined in saturation radioligand binding assays using SKBR-3 cells (1.3 × 106 HER2/cell).
(B ) The binding affinity was calculated at −8.9 kcal mol−1.
The binding affinity was calculated at −8.9 kcal mol−1.
The binding affinity of 4-[18F]FEBZA wassessedsed using a homologous competitive binding assay.
Based on these, energetically favorable and unfavorable contributions to the binding affinity can be assessed on an atomic level.
