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Basic scientific enquiry showed that Aflibercept has a binding affinity to various types of VEGF and also to Placental Growth Factor resulting in higher efficiency [ 3, 4].
Alternative splicing in domain III in FGFR1 3, not FGFR4, creates isoforms (IIIb and IIIc) with varying binding affinity to various FGF ligands (Katoh and Katoh, 2009).
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Telmisartan is a specific AT1 receptor blocker with the strongest binding affinity to AT1 receptor among various ARBs [ 9] and is a partial agonist of peroxisome proliferator-activated receptor- γ (PPAR- γ) [ 10].
It is likely that thymocytes express different FZD receptors with various binding affinity to the existing Wnt proteins within the thymic microenvironment.
The uptake rates of Mitoxantrone in the presence of various substrates were evaluated as an in vitro screening index for comparison of their binding affinity to BCRP.
f Mutant LoNA showed diminished binding affinity to NCL.
FTC-146, SN-56 and Vesamicol binding affinity to VAChT.
SP20 has nanomolar binding affinity to PKAc.
However, why immune cells express different Group 1 LILRs with various binding affinities to a broad range of HLAIs and what is the important role of LILRA3 in macrophages must be addressed in the future.
The photounbinding performance of four CaM binding peptides with different binding affinities to calmodulin - spanning three orders of magnitude - were compared at various laser intensities.
These mSlo1/β4 mutant channels also display higher binding affinities to ChTX than mSlo1/β4 channel.
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