Sentence examples for binding affinity to that from inspiring English sources

The beluga AHR has been cloned, expressed, and shown to bind 2,3,7,8-tetrachlorodibenzo 2,3,7,8-tetrachlorodibenzoinducer) with a similar binding affinity to that of the C57 strain mouse (Jensen and Hahn 2001).

The purpose of this study was to generate low molecular weight Fab and F ab' 2 fragments of the CAIX-targeted chimeric antibody cG250, to compare their CAIX binding affinity to that of intact cG250 and to evaluate their potential as imaging agents in a xenograft tumor model with heterogeneous CAIX expression, as a prelude to using one of these agents for clinical imaging CAIX in hypoxic tumors.

This may compensate for the small saccharide moiety and provide MEL-A with a similar binding affinity to that of GM1.

This hypothesis is consistent with the results obtained with the analogous bisbenzamidine bis-allyl derivative 6, which, in contrast to ©3, displays comparable binding affinity to that of the unprotected amidinium derivative 3 (K d [ 6] ≈ 0.5 μM, see ESI †).

Based on ITC data, AtLYK5 has similar chitooctaose binding affinity to that of wheat germ agglutinin (WGA) while, under the same conditions, AtCERK1 showed extremely low chitooctaose binding activity.

In the development of the growth hormone receptor antagonist Peg-Visomant (Somavert™), this need was overcome by further engineering the site 1 binding site, with eight additional amino acid substitutions, restoring the receptor binding affinity to that of native growth hormone [ 28].

The relatively long half-life for 25(OH)D3 (10 40 d) is in part determined by the molar excess of vitamin D-binding protein (DBP) and strong binding affinity to DBP that protects 25(OH D from degradation and provides a circulating store of vitamin D. Vitamin D metabolites with lower binding affinities for DBP have shorter half-lives.

Also, sensors that use filamentous phages may be useful in B. anthracis spore identification, and wireless magnetostrictive sensors showed binding affinity to B. anthracis that was better than to B. cereus and to B. subtilis spores [ 82].

It has been well documented that the fluorescence intensity of this probe decreases with ATP content due to its higher binding affinity to ATP than that to ADP (Leyssens et al., 1996; Bernstein and Bamburg, 2003).

Furthermore, we anticipated that a minimal ratio of the polyamide DBD would be required because of its exceptionally high binding affinity to DNA and that the ratio of AD be doubled in order to mimic the potent endogenous TF p53.

In contrast, one alanine substitution caused a faster on-rate and slower off-rate, and increased the binding affinity to three times that of the wild-type TCR.