Sentence examples for binding affinity to hydroxyapatite from inspiring English sources
Bisphosphonates (BPs) are the most widely utilized bone-targeting ligand due to exhibiting high binding affinity to hydroxyapatite mineral.
Bisphosphonates have a high binding affinity to hydroxyapatite in bone and are therefore taken up preferentially by the skeleton.
The binding affinity to hydroxyapatite determines attachment to bone and duration of effect, and the inhibition of FPP synthase determines antiresorptive potential.
It has the highest binding affinity to hydroxyapatite and the highest skeletal uptake 68 and is the most potent osteoclast inhibitor.
Bisphosphonates have a high binding affinity to hydroxyapatite, are internalized by osteoclasts through endocytosis, and inhibit bone resorption by cellular effects that impair osteoclast recruitment, differentiation, and action on the bone surface (Chapurlat and Delmas 2006).
Based on the fact that ALN has a high binding affinity to the bone mineral hydroxyapatite (HAp) [ 31, 32], we fabricated ALN/BCP scaffolds by simply mixing BCP scaffolds with ALN.
The agent demonstrates potent binding affinity to autopsy confirmed AD homogenates and the binding affinity constant is superior to that of [18F]-AV-4541, [18F]-Florbetaben40, and [18F]-Flutemetamol42 [18F]-Flutemetamol42 displaCompetitiveriments indicate that [18F]-9 tracer targets the high affinity binding site on Adisplacements, visualizexperiments-PindicateEthataging (data not shown).
The binding interactions of compounds with high binding affinity to Bcl-2 protein were analyzed.
Predictions of binding affinity to a given substrate are based on similarities in binding-site signature.
