Sentence examples for binding affinity that results from inspiring English sources

The salient point of those studies with respect to the current work is that soluble peptides and proteins often produce differential inhibition of calcite steps due to step-specific binding affinity that results in shape modification similar to that seen in Figure 3.

The effect of the S215H and N59D/A158T/S215H substitutions on the activation by MgADP could not be determined because of a dramatic drop in MgADP binding affinity that resulted from the S215H substitution.

Enrichment of N-BAR domain proteins at curved membranes is thus believed to be due to an increase in binding affinity that may result molecularly from a reduced off-rate and possibly an increased on-rate.

Considering the enhanced enzyme binding affinity that had resulted from the presence of a 3-cyano or 3-sulfonyl group on the phenyl ring in the disubstituted variants (Table 2), these substituents were introduced into the trisubstituted pyrimidines aiming for a corresponding increase in enzyme potency and activity against M. tuberculosis.

Overall, this resulted in a binding affinity that is quite similar to that in aqueous solutions.

The simulation results also revealed that there is a range of cytokine binding affinities that would achieve optimal therapeutic efficacy.

Glycosylation with a disaccharide on C3 position of flavonol results in higher binding affinity than that with monosaccharide.

Our binding affinity results obtained from insertion and deletion are very similar indicating that our simulations are well converged and that accurate estimates of binding affinities were obtained.

It is thought that the binding affinity is the result of molecular contacts within the 15-mer and that the longer peptides will bind to the molecule in a register with the most favorable contacts.

However, combined with the comparable high correlation coefficients between the PharmDock predicted binding energies and the experimentally measured binding affinities, this result suggests that a good prediction in the overall correlation does not guarantee a good ranking power for the ligands bound with the same protein.

Finally, a heptapeptide is designed for a protein that has excellent binding affinity according to AutoDock results.