Sentence examples for binding affinity such that from inspiring English sources

However, the detection of bitter taste must accommodate the broad diversity of chemical structures found in nature while simultaneously being tuned to an optimal sensitivity and binding affinity such that not all food substances taste overwhelmingly bitter.

The sites missing from the gold standard are likely to be minor variants of the motif with slightly lower binding affinity, such that the experimental methods for identifying protein to DNA binding sites overlook them.

Using activity types that act as a measure of binding affinity, such as I C50 or K i, and applying activity value cut-offs, it is possible to identify molecules which have higher binding affinity to certain targets compared to others.

Ligand binding assays quantify the binding affinities such as Kd or IC50 values.

The structural conformation and physicochemical properties of both the ligand and its receptor site determine the level of binding affinity that is observed in such an interaction.

4b Even when high affinity peptides are discovered, additional experiments are needed to obtain quantitative metrics, such as equilibrium binding affinity constants (Kd) that help describe the physical properties of the peptide protein interaction.

Affinity measurements using related PC-phenyl analogues, including peptides of varying lengths, demonstrate that carrier determinants contribute to binding affinity and that somatic mutations alter this recognition.

Presumably such peptide residues with few intermolecular interactions contribute relative little to the overall peptide-MHC binding affinity so that such docking errors do not dramatically reduce binding affinity prediction performance.

Receptors are proteins that have specific binding affinity for substances that produce a physiological event in the body.

Moreover, it is unlikely that attenuation of IKKβ binding affinity of such similar magnitude would occur with two disulfides at such different locations within the NEMO structure.

That is to say, these small synthetic peptides might not bind to hβ4-loop at a binding affinity similar to that of BKα subunit binding to hβ4-loop.