Sentence examples for binding affinity shown by from inspiring English sources

The differences in nucleotide binding affinity shown by mutants V250A and V250F with respect to the wild-type DNA polymerase agree to a role for Val250 as a metal B dNTP complex ligand.

The binding affinity shown at the enzyme level was further corroborated by biophysical characterization techniques.

This inhibition was correlated with peptide-binding affinity to CaM, i.e., higher CaM-binding affinity showed more potent inhibition.

Our results showed that the SNPs identified in multiple cancer types can alter TF binding affinity as shown by significant changes in PWM scores.

The beads-attached tetrapeptides with high affinities to the EGFP-Src SH2 domain showed more fluorescence intensity than those beads containing tetrapeptides with weak binding affinities, as shown by fluorescence microscopy and fluorescence imaging system.

Paralogous and orthologous TFs tend to have highly similar DNA-binding affinities, as shown by the highly similar motif logos at the leaves of the motif tree in Figure 5.

Although the charged amino acids in Cluster III of the ligand are distributed in a highly complementary manner, these residues do not contribute to the binding affinity, as was shown by mutagenesis and BIAcore analysis [ 39].

The docked pose of 5d with highest binding affinity is shown in Fig. 8.

The retinoblastoma binding protein 46 (RbAp46) was initially identified as a Rb binding protein, as shown by Rb affinity column studies [ 14].

Thermostabilising mutations in GPCRs selected using a radiolabelled antagonist resulted in a thermostabilised receptor preferentially found in an antagonist binding conformation, as shown by the affinity for antagonists that was unchanged, whereas the affinity for agonists was orders of magnitude weaker than for the wild type receptor.

It apparently binds to the high-affinity Asc binding site as shown by Rocklin et al. (2004).