Sentence examples for binding affinity showing that from inspiring English sources

The presence of TRAX resulted in a 3-fold reduction in PLCβ1- Gαq-GTPγS binding affinity, showing that TRAX competes with Gαq for binding to PLCβ1 (Fig 3a).

The variation of binding affinity showed that anchors at positions 1, 3 and 5 in the frame of TP5 actually interacted with the receptor HLA-DR; however, anchor at position 2 primarily involved in steric constraints.

Of note, in vitro measurement of the DNA-binding affinities shows that the (SCL E12 bHLH LMO2 LDB1LID complex binds palindromic and nonpalindromic E box motifs with lower affinity (between 3.7- and 1.5-fold) than (SCL E12 bHLH (KΔ = 4 × 10 M−1 versus KΔ = 1.5 × 10 M−1 for CAGCTG, and KΔ = 1.7 × 10 M−1 versus KΔ = 2.5 × 10 M−1 for CAGGTG) (Ryan et al., 2008).

Repeated analysis of peptide-HSP72 binding affinities showed minimal between-trial variation that was associated with reductions in HSP72 binding capacity with time and/or repeated use.

Results of the binding affinity assay showed that FGF-Trap displayed a Kd of approximately 1.4 × 10−3 p M. To examine the pharmacokinetic properties of FGF-Trap, FGF-Trap was intraperitoneally injected into BALB/c nude mice.

The chloride-binding affinity assay showed that the Kd was 10.40 mM for the S262A -HwHR, comparable with HsHR.

Sequence analysis revealed amino-acid substitutions in the Lat B-binding site in one of the suspensor-specific actin isoforms, which may result in a different binding affinity for Lat B. We show that manipulating actin in specific cell types in somatic embryos using Lat B treatment accelerated and even synchronized the development of somatic embryos and may be of practical use in biotechnology.

We focused on the ligands with highest binding affinity and show that both Activin A and GDF11 but not Activin B or BMP10 play an important role in erythropoiesis.

The calculated and experimental binding affinities correlate well, showing that MP-CAFEE can accurately rank the compounds with diverse scaffolds.

It is most unlikely due to differences in affinities since in an in vitro binding assay, James et al. showed that affinities of DPA-714 and PK11195 for TSPO are comparable [affinity of DPA-714 (Ki = 7.0 ± 0.4 nM); affinity of PK11195 (Ki = 9.4 ± 0.5 nM ] [ 20].

Fluorescence binding results are showing that molecule TPUI has an excellent binding-affinity for CAIX (kD = 0.048 μM).