Sentence examples for binding affinity predicted by from inspiring English sources
This ligand exhibited improved binding affinity predicted by means of free energy calculations.
The correlation coefficient r indicates the level of correlation between the binding affinity predicted by our models and the affinity measured by biochemical experiments.
The absolute binding free energies were estimated by the linear interaction energy approach and compared with the binding affinities predicted with docking.
Experimental characterization of the five mutants by NMR spectroscopy confirmed the binding affinity pattern predicted by BP-Dock.
The peptide binding affinities were predicted by first predicting whether or not each 9-mer fragment binds; if at least one was predicted to bind then the peptide was classified as a binder, otherwise it was classified as a non-binder.
A plot of Δ Tm versus FB FL reveals a good correlation between the binding affinity for Kef predicted by the DNGSH-based fluorescence competition assay and Δ Tm observed using DSF.
Supplementary Data 2 lists the 69 different transcription factors whose DNA binding affinity was predicted to be affected by the 251 selected HGMD regulatory SNPs/mutations from the 13 different disease states under study.
Indeed, our hypothesis can be validated experimentally; by changing the Gcn4p binding site for gene ILV5 to have a lower binding affinity, it predicts that the regulation of the amino acid biosynthesis pathway will be disrupted more easily.
However, the high correlation between measured binding affinities and predicted binding affinities illustrated the power of using such methods of support vector machines on small sample sizes.
Further analysis with leverage plots demonstrated that binding affinity in human and canine prostate tissue is best predicted by binding affinity to recombinant bovine alpha-1C (P <.01 human and P <.001 canine).
To prioritize functional SNPs, we examined the relative regulatory potential by comparing cancer to normal cell lines where data is available (detailed in Methods) and differences in predicted TF binding affinity by comparing major and minor alleles.
