Sentence examples for binding affinity of this from inspiring English sources

The IL-1F10 gene locus was mapped to human chromosome 2. Recombinant IL-1F10 protein binds to soluble IL-1RI, although the binding affinity of this novel IL-1 family member is lower than those of IL-1Ra and IL-1β [ 32].

Maintenance of the high binding affinity of this ATP aptamer and the observation of two separate Kd's for ATP binding indicate NSET as an effective, nonmanipulative, optical method for tracking biomolecular changes.

Isothermal titration calorimetry methods show that the binding affinity of this new sequence is slightly tighter than the existing cocaine-binding aptamer.

Receptor binding affinity of this novel fluorescein-ghrelin(1 18) was similar to that of wild-type ghrelin and a synthetic GHS-R1a ligand, hexarelin.

The additional H-bonds with the oxygen of the amide and/or H of NH of the amide with the amino acid residues may be responsible for the higher binding affinity of this group of compounds towards COX-2.

The binding affinity of this compound towards GyrB protein was analysed by differential scanning fluorimetry which resulted in a positive shift of 3.3 °C in melting temperature (Tm) when compared to the native protein thereby reacertaining the stabilization effect of the compound over protein.

However, the fact that further methylation of tricin constitutes ca. < 5% of total methylation (Additional file 4B), may be due to the weak binding affinity of the enzyme to this substrate, steric hindrance of the bulky methyl group, or the competitive inhibition of the enzyme reaction by the final product, trimethyltricetin (unpublished data).

The true IGF-I concentrations are approximately twofold higher than the results obtained using the immunoassay, most likely because of a lower binding affinity of the labeled antibody in this human IGF-I immunoassay.

Some of our previous work has shown that increased PBAE polymer molecular weight can increase the binding affinity of the polymer with DNA and this can improve gene delivery efficacy.

We have added the following sentence to note this: 'The binding affinity of the PfRh5-C basigin interaction was determined by surface PfRh5-C basigince (SPR) to be KD= 43.4 nM.

This, in turn, increases the binding affinity of the intracellular domains of the receptor for arrestin proteins.