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Such analyses indicate that the cationic head of the different compounds must be refined in order to obtain an increase in the binding affinity of these ligands.
The binding affinity of these compounds for human MT1 and MT2 receptors was determined using 2-[125I]-iodomelatonin 2-[125I]-iodomelatonin 2-[125I]-iodomelatonin
Using a major probe and a minor probe containing the A allele and G allele, respectively (Table S5), we performed an EMSA to evaluate the binding affinity of these alleles for unknown transcription factors in 293T cells.
According to the current results and further evaluating the available literature, we propose that there are many more unknown factors (apart from mannan and glucan content) influencing binding affinity of these pathogens.
In this study, we report on the adsorption of RNA and DNA molecules by exploiting the high binding affinity of these nucleic acids to Ag+ ions anchored on magnetic poly(glycidyl methacrylate) (PGMA) microparticles.
This is consistent with benzylidene anabaseine analogs with OH and NH2 functional groups showing the highest binding affinity of these congeners, and the position of the ligand shown in previous X-ray crystallographic studies of ligand-Ac complexes.
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However the binding affinities of these peptides did not exceed substantially that of NCPERIITL, the most affine peptide tested in the original peptide set (pBL50(exp) = 7.120).
The binding affinities of these bivalent ligands for ERα and ERβ were determined.
Gel-mobility shift assays revealed very strong binding affinities of these PNAs.
The binding affinities of these small molecules with P70-S6K1 & PI3K-δ were performed using AutoDock Vina.
First, the binding affinities of these three molecules were assessed, then we obtained the crystallographic structure of a tubulin-TH complex.
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