Sentence examples for binding affinity of specific from inspiring English sources

Importantly, starting from this type of graphic, the differences can be traced to the effects of amino acid mutations on the binding affinity of specific alleles.

Notably, the ultra-affinity concept proposed here shares some similarities with the well-known kinetic proofreading (Hopfield, 1974) since in both cases chemical energy consumption is used to increase the binding affinity of specific molecules beyond their equilibrium value.

Secondly, the specificity of substrates of HSulf-2 -HSPGs located at the cell surface could contribute to the differential response to the presence of HSulf-2 based on the binding affinity of specific HSPGS towards different growth factors.

We evaluated the long-term effects of neonatal exposure to OH-PCBs with treatment doses that were based on the reported binding affinity of specific OH-PCB congeners to estrogen receptor α. BALB/cCrgl female mice were treated within 16 hr after birth by subcutaneous injections every 24 hr, for 5 days.

The first step to achieve this goal is to understand the molecular basis of high binding affinities of specific pro-apoptotic BH3 peptides for Mcl-1 and A1.

83– 85 The relation of binding affinities of specific IgE epitopes on the physiological effect has been directly tested using a panel of recombinant IgE (rIgE) antibodies.

These matrices enable people to assign a quantitative score to any sequence to evaluate the binding affinity of the specific TF at that sequence.

We believe that this discrepancy between our experimental observations and simulation results is primarily due to steric hindrance, where macromolecular crowding effects on the resin surface decrease the binding affinity of the specific aptamer sequence; a similar phenomenon has been reported for the binding of soluble proteins to surface lipid vesicles.

Low binding affinity of carbohydrate-specific IgE antibodies was previously ruled out [9].

The results of this study suggested that the binding affinity of substrates to specific receptors or efflux proteins is not entirely dependent on a particular variable or an individual group of variables in the relationship, but it is rather affected by various combinations of variables.

We then used this luminescence signal to measure the binding affinity of Tb3+ to specific sites on SbpA.