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By combining the most favorable substitutions we increased the binding affinity of paclitaxel 500-fold.
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The binding affinity of docetaxel for the beta-tubulin sub-unit is 1.9, versus 1.0 for that of paclitaxel.
The binding affinity of 4-[18F]FEBZA wassessedsed using a homologous competitive binding assay.
Due to different binding mechanisms, the binding affinity of various TSPO radioligands may vary significantly.
Competitive ligand-binding assays measure the binding affinity of a substance to an (isolated) receptor.
This binding is explained by the broad binding affinity of lectin.
Mal III has the highest binding affinity, whereas the binding affinity of Mal II and Mal IV are nearly identical and the binding affinity declines from Mal V to Mal VII.
Third, the assay employed by Metushi et al. [42] monitored the binding affinity of the peptide towards the HLA, not the actual binding affinity of the drug.
We also confirmed the binding affinity of BODIPY-BBN 5 using [125I-Tyr4]bombesin [125I-Tyr4]bombesinnding assay (Fig. 4b).
To assess binding potential in humans, a simple blood test now evaluates the binding affinity of platelets for 11C-PBR28 [35]. 11C-PBR28 [35]
Antibacterial activities and DNA binding affinity of this class of cadmium complexes have attracted considerable interest.
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