Sentence examples for binding affinity of human from inspiring English sources
The binding affinity of human CYP24A1 for A-ring diastereomers was (1α,3β) > (1α,3α) > (1β,3β) > (1β,3α), indicating that both hydroxyl groups at C-1 and C-3 positions significantly affect substrate-binding.
For example, this plasticity could slightly modulate the binding affinity of human CNTN5 and -6 for PTPRG and thus modify its intracellular phosphatase activity.
Glycoengineering is a process used to manufacture antibodies lacking core fucose, which results in significantly higher binding affinity of human IgG1 antibodies to human FcγRIIIa, and consequently greatly enhanced ADCC activity.
Comparison of the azole-bound structures provides insight into the relative binding affinities of human and bacterial P450 enzymes to ketoconazole and fluconazole, which can be useful for the rational design of antifungal compounds and specific modulators of human CYP51.
The binding affinities of human histamine H3 antagonists were predicted using an enhancement replacement method – partial least squares (ERM-PLS) model and the results were compared with those of genetic algorithm (GA -PLS and stepwise linear reGA -PLSn (SW)-PLS models.
This RNA oligonucleotide (wildtype NRE1) was identical in sequence to one used in a previous study that analyzed the binding affinity of the human PUM-HD to RNA [ 14].
Our data clearly indicate that residues 125 and 140 play critical roles governing the differential AZ-binding affinities of human ODC and AZI.
We tested the binding affinities of the peptides natGa-DOTATOC, natGa-DOTATATE and natGa-NODAGA-JR11 to human sstr2 in a filtration-based, competition binding assay.
Using prototypic pandemic strains, such as 1918 H1N1 and 1957-58 have, we have previously demonstrated that the binding affinity of HA to human receptors is one important factor that correlates with the transmissibility of the virus via respiratory droplets in ferrets [10], [11], [12].
3 Sato et al compared the binding affinity of tamsulosin for human α1-AR subtypes with that of other α1-blockers, ie, silodosin, terazosin, alfuzosin, and naftopidil.
