Sentence examples for binding affinity of diverse from inspiring English sources
The performance of several structure-based design (SBD) approaches in predicting the binding affinity of diverse small molecule inhibitors co-crystallized to human renin was assessed to ascertain the modeling tool and method of choice required when dealing with structure-based lead optimization projects.
Considering different DNA extraction methods for Chinese and Caucasian samples, the ethnic differences seen in genomic coverage may be partially due to different binding affinities of diverse DNA extracts to the SNP chip array.
We compare the in vitro inhibitory properties and binding affinity of ten diverse compounds with all four family members, and present the crystal structures of the KDM5A-linked Jumonji domain in complex with eight of these inhibitors in the presence of Mn II).
We show that this flexibility is essential in order to correctly model the binding affinity of a set of diverse ligands.
The molecular basis of the effect of smoke may be related to the diverse binding affinity of the active compounds to the proposed receptor and the consequent effects exerted on the changes of gene expression patterns.
The hypothesis that diverse ESAG repertoires could facilitate trypanosome infection of diverse mammalian hosts was first proposed for ESAG6 [ 27], where different sequence polymorphisms affect binding affinity of the transferrin receptor to variable transferrin molecules [ 39].
However, the binding affinity of PDZ domains is known to be regulated through allosteric interactions49.
(B) The binding affinity of NADH toward LDHA was analyzed using Cibacron Blue as a mimicking probe of NADH.
Similarly, the binding affinity of pyruvate to LDHA in the presence of PSTMB was examined using 14C radio-labeled pyruvate.
This, in turn, increases the binding affinity of the intracellular domains of the receptor for arrestin proteins.
