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This result indicates that V318D may weaken the binding affinity of colchicine to β-tubulin.
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All the structures were docked to colchicine binding site of β tubulin for examining the binding affinity of compounds for antitumor activity.
This binding is explained by the broad binding affinity of lectin.
The binding affinity of 4-[18F]FEBZA wassessedsed using a homologous competitive binding assay.
Due to different binding mechanisms, the binding affinity of various TSPO radioligands may vary significantly.
Competitive ligand-binding assays measure the binding affinity of a substance to an (isolated) receptor.
However, the DNA binding affinity of TTE-MΔc102S1 TTE-MΔc102S1han wasd type complex DNA binding affinity (Figure 4A).
The binding affinities of S9 or colchicine to the tubulin were determined using the SPR biosensor technology.
The binding affinities of the designed tripeptides are all superior to the binding affinities of their known tripeptide ligands.
5b promoted tubulin polymerization and this was supported by the docking studies, wherein 5b showed significant binding affinity at the colchicine binding pocket of tubulin.
ROBO1-binding affinity of the anti-ROBO1 MAb.
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