Sentence examples for binding affinity of an from inspiring English sources
Nevertheless, it was reported that multivalent binding avidity can be kinetically limited if the binding affinity of an individual receptor-ligand pair is too tight [44, 45].
Furthermore, we provide in a dose-response paradigm, the details of the effects of these derivatives in modulating agonist-induced β2AR activities (G-protein-mediated cAMP production and β-arrestin recruitment to the receptor) as well as the binding affinity of an orthosteric agonist in radio-ligand competition binding assay.
This work reveals that any increase in the binding affinity of an aptamer over a free peptide is dependent on the increase in the favorable enthalpy of binding, which is ideally caused by stapling of the peptide or by additional interactions between the aptamer protein and its target.
Conformational changes of the intact channel following ligand binding shape the apparent binding affinity determined with electrophysiology [20], therefore, the binding affinity of an isolated region might differ from that of the intact channel.
This type of assay has been used as an indirect method to estimate the binding affinity of an antibody [ 42].
It has been established that QCM-D is a reliable method to evaluate the binding affinity of an enzyme toward its substrate [ 32, 33].
And the binding affinity of a compound to a protein in the pathway network was assessed by molecular docking.
The binding affinity of a given agonist towards its target GPCR depends on which state the receptor is in.
However, cell-binding assays require specific considerations to accurately quantify the binding affinity of a protein protein interaction.
Herein, we designed, synthesized and evaluated the binding affinity of a series of bitopic ligands: arypiperazine-phenyl-1,2,4-oxadiazoles.
