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P1 showed low and non-specific binding affinity for metal ions (Ca2+, Zn2+, Na+, or Li+) in water whereas P2 did not exhibit any significant interaction with these ions.
The protein is essential for RNase P function in vivo and plays an important role in substrate recognition, the stabilization of the RNA's tertiary structure, and increases the binding affinity for metal ions crucial for substrate positioning and catalysis [3,32].
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In this process, a water-soluble polymer with strong binding affinity for the target metal ions is added to contaminated water.
This is also consistent with the reported binding affinity for the catalytic metal.
The weak metal binding affinity for this variant results from clashing steric interactions within the metal coordination sphere.
Additionally, molecular docking results showed a strong binding affinity for compounds 1 3 through chelation between copper metal and ligands.
Binding affinity in both human and canine prostate most significantly correlated with binding affinity for the recombinant bovine alpha-1C receptor (r =.98 human,.95 canine).
The presence of the toxic enzyme inside the cocoon is essential for its subnanomolar binding affinity for the TcA subunit.
One mutant, MR1-1 scFv), had increased specific binding affinity for EGFRvIII.
c Targets detected with no significant binding affinity for CIS22a.
Molecular dynamics (MD) simulations are performed using constraint polypeptides that were combinatorially selected to have binding affinities for the noble metal platinum (Pt).
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