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Zoledronate has a high binding affinity for bone mineral (Nancollas et al 2006).
The relatively long duration of action of zoledronic acid is attributable to its high binding affinity for bone mineral.
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Although its mechanism of action on bone is not yet fully understood, it is likely that the positive effects of this isoflavone are a direct consequence of a greater binding affinity for the ER-β, compared with that for ER-α, causing positive effects on bone during the mineralization phase (Messina et al., 2004; McCarty, 2006).
c Targets detected with no significant binding affinity for CIS22a.
Moreover, the phosphorylation modification of FUNDC1 affects its binding affinity for LC3B and regulates selective mitophagy.
Bis-DOTA-hypericin had a selective binding affinity for PS and PE phospholipids [45].
The tetradecapeptide bombesin (BN) shows high binding affinity for these BN2/GRP receptors.
These VHHs were selected based on their specificity and binding affinity for their targets.
We show that type II binding can have a profound influence on binding affinity for CYP3A4, and the difference in binding affinity can be as high as 1200-fold.
Our molecular docking platform explored the binding association of various drugs inside the binding pocket, but did not analyze the peptide's binding affinity for these drugs.
SC alone exhibited negligible binding affinity for Ang2.
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