Sentence examples for binding affinity for an from inspiring English sources
The immunoglobulin binding affinity for an encountered antigen is dynamically optimized in the process of affinity maturation that takes place in germinal centers.
Strep-tag II has a strong binding affinity for an engineered streptavidin derivative called Strep-Tactin, which enables fast and simple one-step purification [34].
Conversely, Bub3 did not show any binding affinity for an unrelated phospho-peptide.
A score of "1" may be interpreted as intermediate or normal binding affinity for an insulin or a similar diabetogenic peptide.
In one study we found that TTP could serve as a substrate for the p38 protein kinase and that global dephosphorylation of TTP in a cell-free system with alkaline phosphatase seemed to increase its binding affinity for an ARE-containing RNA substrate [ 42].
We applied this method to examine the binding affinity for a series of published cyclin-dependent kinase 2 (CDK2) inhibitors.
The internal potential (strain) energy of a drug molecule is a key component of the binding affinity for a drug to a protein.
In the simplest case, this includes an on/off switching of the binding affinity for a certain guest, but more sophisticated consequences such as fine-tuning of the binding kinetics or regulation of guest specificity can be achieved.
Systematic Evolution of Ligands by EXponential enrichment (SELEX) is an experimental procedure that allows extraction, from an initially random pool of oligonucleotides, of the oligomers with a desired binding affinity for a given molecular target.
This adaptation requires the development of methods for (i) generating candidate structures and (ii) evaluating and prioritizing these structures with respect to their binding affinity for a specific guest.
Given a training dataset of continuous binding affinities and the similarities among drugs and among targets, SimBoost constructs features for drugs, targets, and drug target pairs, and uses gradient boosting machines to predict the binding affinity for a drug target pair and to generate a prediction interval.
