Sentence examples for binding affinity for a from inspiring English sources
In the simplest case, this includes an on/off switching of the binding affinity for a certain guest, but more sophisticated consequences such as fine-tuning of the binding kinetics or regulation of guest specificity can be achieved.
Systematic Evolution of Ligands by EXponential enrichment (SELEX) is an experimental procedure that allows extraction, from an initially random pool of oligonucleotides, of the oligomers with a desired binding affinity for a given molecular target.
This adaptation requires the development of methods for (i) generating candidate structures and (ii) evaluating and prioritizing these structures with respect to their binding affinity for a specific guest.
As a DNA cleavage domain, we chose an analogue of the metal-binding loop (12 amino acid residues), peptide P1, which has been reported to exhibit a strong binding affinity for a lanthanide ion and DNA cleavage ability in the presence of Ce(IV).
We applied this method to examine the binding affinity for a series of published cyclin-dependent kinase 2 (CDK2) inhibitors.
The internal potential (strain) energy of a drug molecule is a key component of the binding affinity for a drug to a protein.
The immunoglobulin binding affinity for an encountered antigen is dynamically optimized in the process of affinity maturation that takes place in germinal centers.
Strep-tag II has a strong binding affinity for an engineered streptavidin derivative called Strep-Tactin, which enables fast and simple one-step purification [34].
A score of "1" may be interpreted as intermediate or normal binding affinity for an insulin or a similar diabetogenic peptide.
Although VEGFR-1 has a 10-fold higher binding affinity for VEGF-A, its activation has less of an impact on the activation of intracellular signalling intermediates than VEGFR-2 (Waltenberger et al, 1994).
