Sentence examples for binding affinity following a from inspiring English sources

ID2 and the other shorter clone variants, as well as N-terminally elongated SmDia variants demonstrated a nearly gradual decrease in binding affinity following a Gaussian-like distribution.

We speculate that the apparent loss of metal B binding affinity following strand transfer is caused by the ejection of the newly formed phosphodiester form the active site.

To calculate binding affinity of a test set in pKi, following equation was used in DS: pKi = A+(B vdW) + (C c+pol)−(D BuryPol2).

The percentage data were converted into an equivalent binding affinity kA with the following formula (Eq. (6)) derived from the law of mass action.

Competitive ligand-binding assays measure the binding affinity of a substance to an (isolated) receptor.

The average affinity of a drug/target captures their typical binding behavior, which is valuable to predict the binding affinity with a specific target/drug.

Peptides were assayed for binding affinity using a filtration-based competitive assay to sstr2.

Conformational changes of the intact channel following ligand binding shape the apparent binding affinity determined with electrophysiology [20], therefore, the binding affinity of an isolated region might differ from that of the intact channel.

In order to determine the binding affinity, a competitive cell binding assay was performed.

Replacement of the aminopyrazole head group with an aminopyridine led to an initial loss in binding affinity, but this was regained following optimisation, and selectivity against a human kinase panel was improved.

However, binding affinity to BMPs remains similar following cleavage [ 10], which suggests that the change in BMP-inhibitory activity is not necessarily the result of conformational change.