Sentence examples for binding affinity followed by from inspiring English sources

As such, the human PGRN588 593 has the highest binding affinity followed by NTS and then the mouse Pgrn584 589.

In vitro selection experiments for histone-DNA binding affinity, followed by direct measurements of free energies of nucleosome formation, indicate that nucleosome free energies fall within a range of several kcal/mol [ 13- 15].

The integrin αvβ3/αvβ5 binding affinity followed a general trend: FITC-Galacto-RGD2 ∼ FITC-3P-RGD2 > FITC-RGD2.

This observation can have two reasons: Firstly, toxins bind to sites with higher affinity, followed by binding to lower affinity sites, when toxin concentration increases (Ferraz et al.2004).2004

KO_Pax denotes the binding affinity of Olig2 for the Pax6 enhancer; other TF to TF binding affinities follow the same notation.

A simple G-quadruplex containing only two tetrads [thrombin binding aptamer (TBA)] was first studied using α-HL regarding its cation affinities, followed by the studies of thrombin TBA interactions.

To isolate the kinases detected in the in-gel assay, GST-bZIP63 was immobilized on GST-Sepharose and plant protein extracts made from root cultures or root-derived cell suspension (as the latter is maintained in the presence of sucrose, please specify which of these sample is shown in Figure 2) were subjected to affinity binding followed by NaCl elution.

In contrast, hnRNPH represses splicing when bound to exons (Chen et al, 1999; Mauger et al, 2008), as shown here with MADD and RON, by antagonizing activities from nearby enhancers, by directly interfering with spliceosome components or by nucleating a silenced region through high-affinity binding followed by RNA propagation, as proposed for hnRNP A1 (Okunola and Krainer, 2009).

We present a structure-based method for predicting class II epitopes that combines molecular mechanics docking of a fully flexible peptide into the MHC binding cleft followed by binding affinity prediction using a machine learning classifier trained on interaction energy components calculated from the docking solution.

In this report, we provide the first crude insight into the structural organization of the human dopamine transporter (hDAT) based on the identification of an endogenous high affinity Zn2+ binding site followed by engineering of an artificial Zn2+ binding site.

Src– and Hck ligand substrate complexes were generated by incubation of SFKS245C with 6 or 7. Excess small molecule was removed through Ni-affinity resin binding followed by desalting.