Sentence examples for binding affinity does not from inspiring English sources

It has been shown that binding affinity does not increase linear with the molecular size [2].

However, analgesic potencies vary more than 30-fold across the compounds, and in vitro binding affinity does not predict in vivo potency.

Based on results obtained by SMD and the molecular mechanics-Poisson Boltzmann surface area mechanics-Poisson Boltzmann25489 can be usurfacetreareaot only wild-type but also tamethodresistant N294S, H274Y variants of A/H5N1 virus as its binding affinity does not vary much across these systems.

Obviously, the HLA binding affinity does not have to correlate directly with immunogenicity or antiviral CTL response.

Whilst there is a paucity of information on binding affinity versus ubiquitination, our unpublished observation is that binding affinity does not correlate with ubiquitination, and this is partly validated by the high affinity binding in some cases where ubiquitination is not the final outcome.

In the concrete binding situation many external impacts will influence the folding of the aptamer, so that the structure of the highest binding affinity does not necessarily correspond to the structure yielding minimal free energy.

Interestingly, the K51A, L56A, and M1 mutants that significantly altered the binding affinity did not cause a significant change in the pH threshold of pore formation.

In contrast, flexible ligands with similar binding affinities did not activate Kef.

Indeed, an extensive search through possible combinations of binding affinities did not yield self-limiting growth of small clusters in computer simulations.

Moreover, the observations that their binding affinities do not exceed those determined for T4, and that their interactions are noncovalent, points towards their ability to dissociate from TTR upon delivery to potential target tissues.

Mutations that reduce CD44- and Par3-binding affinity do not affect on PI 3, 4, 5 P3-binding affinity (Supplementary Figure S9A), implying that the PHCCEx domain binds PIs and proteins with no significant interference or cooperativity.