Sentence examples for binding affinity determined with from inspiring English sources

Further, the apparent binding affinity determined with electrophysiology reflects cooperative ligand-binding to the full length tetrameric channel whereas the binding affinity determined with tryptophan fluorescence reflects ligand binding to a monomeric, isolated C-terminal domain and therefore lacks effects of cooperative interactions.

Conformational changes of the intact channel following ligand binding shape the apparent binding affinity determined with electrophysiology [20], therefore, the binding affinity of an isolated region might differ from that of the intact channel.

Stepwise titrations of SL3ESS3 into N-labeled UP1 reveal slow exchange on the NMR chemical shift time scale, consistent with the nanomolar binding affinity determined by calorimetry (Table 1).

The apparent binding affinity of the two flavonoids determined with electrophysiology is higher than the lower limit for the apparent binding affinity determined based on the changes in the fluorescence.

The binding affinity determined for TPP (KD = 0.2 µM) indicates a tighter interaction with Cass2 than has been reported for the fold relative BmrR [27].

Belatacept was labeled with indium-111, and the binding affinity was determined with CD80/CD86-positive CD80/CD86-positive

In vitro GRPR-binding affinities were determined with competitive binding assays on PC3 human prostate cancer cells.

Since TRAX might affect the association between PLCβ1 and Gαq by altering its membrane binding affinity, we determined whether TRAX would interfere with PLCβ1's association with membranes.

LXY30-FITC and S-LXY30-FITC were incubated with U-87MG cells, and the binding affinity was determined by flow cytometry analysis.

HER2 binding affinity was determined in saturation radioligand binding assays using SKBR-3 cells (1.3 × 106 HER2/cell).

The binding affinity for rhGPC3 was established by ELISA at two concentrations of rhGPC3 protein and repeated, with affinity determined by calculation of half maximal binding concentration (EC50) using a non-linear regression curve-fit algorithm.