Sentence examples for binding affinity comparable to from inspiring English sources

IP induced a moderate quenching of the intrinsic fluorescence of H6-NBD1 whereas IDs 9 and 10 showed a binding affinity comparable to the ATP analogue TNP-ATP.

Replacement of the large hydantoin-indole moiety from our previous work with a variety of smaller heterocyclic analogues gave rise to potent CCR5 antagonists having binding affinity comparable to the hydantoin analogues.

Interestingly, DNA binding assay results were in agreement with that of the cytotoxicity assays where the most potent anticancer compounds showed good DNA binding affinity comparable to that of doxorubicin and daunorubicin.

These HSEs have binding affinity comparable to the minimal functional binding sequence as long as they exceed 4 subunits [20].

This is a binding affinity comparable to the pharmaceutical PPARγ agonist pioglitazone (KD = 1,310 nM) and the endogenous ligand arachidonic acid (KD = 1,340 nM), as determined in the same assay (Singh et al. 2008).

Our objective in calculating the PMF for FSite1 and NSite1 is to evaluate whether the F-form albumin conformations locked in the PBSA hydrogels retain atRA binding affinity comparable to N-form albumin.

Equilibrium dissociation constants (KD) obtained using surface plasmon resonance indicate that these fusions have μm binding affinities, comparable to the native knob-containing fibrin fragments.

We confirmed that ZAK and MKK4 (MAP2K4) have high binding affinities comparable to that of the intended target, BRAF (estimated K d below 50 nM) for both PLX4720 (Davis et al., 2011) and vemurafenib, and confirmed activity against MAP4K5 (Bollag et al., 2010) (Tables 2 and 3).

Several peptides binding with affinity comparable to the test autoantigens were identified, including peptides from collagen II α1, collagen XII α1, cartilage-derived morphogenic protein, and adlican for HLA-DR1 and collagen VI α2, laminin α1, laminin α5, and fibronectin for HLA-DR4 (Figure 6b).

We classified dioctyl sodium sulfosuccinate (DOSS), a major component of COREXIT, as a probable obesogen by PPARγ transactivation assays, PPAR-driven luciferase induction in vivo, PPARγ binding assays (affinity comparable to pioglitazone and arachidonic acid), and in vitro murine adipocyte differentiation.

[3H]Hemicholinium-3 binding to the transporter was found in the cell membrane fraction at stages from the unfertilized egg to pluteus, with a binding affinity comparable with that seen in mammalian brain.