Sentence examples for binding affinity can alter from inspiring English sources

These differences in KIR/MHC-I binding affinity can alter KIR signaling and NK cell activity [ 16].

But its binding affinity can be altered by integrating the conformationally favored functional groups at the active site of the ligand-target interface.

Even though these variations were found to have only a modest effect on in vitro switching, they are expected to play a much greater role during infection, where factors such as immune responses and binding affinities can significantly alter the var gene expression profiles.

DNA binding modes and binding affinity can be modulated by ligand design.

This relative binding affinity can then be compared with R values extracted from other images.

We show that type II binding can have a profound influence on binding affinity for CYP3A4, and the difference in binding affinity can be as high as 1200-fold.

Biochemical assays of binding affinity can be developed into a high-throughput screen.

The relative binding affinities can be simultaneously determined.

Moreover, the 3D location of substituted amino acids shed light on the implied impact on the protein's function: An exchange of buried residues may, for example, affect protein stability and folding, whereas mutations located on the protein surface, close to putative binding sites can alter binding affinities.

Apart from its effects on microtubule binding, phosphorylation can alter tau subcellular localization to dendritic spines (127) or can alter its affinity for the plasma membrane (128), thereby causing alterations in synaptic function (127, 129).

Hence, in addition to photoisomerization-dependent changes in the affinity of the receptor, guest binding can alter the kinetics of the photoisomerization process.