Sentence examples for binding affinity attributed to from inspiring English sources

Comparison of the binding kinetics and thermodynamics between the glycosylated and deglycosylated murine mAb 18B7 forms and the chAb 18B7 revealed differences in binding affinity attributed to the heterologous CH region, however no contribution from the carbohydrate motif was observed.

It was previously reported that truncated RyR1 without the C-terminal 15 amino acids lacks high-affinity ryanodine binding that was attributed to impaired tetrameric assembly [ 9], although it is possible that the deletion could have directly affected the ryanodine-binding site.

We are not aware of other systems where binding affinity trends have been attributed to long-ranged electrostatic desolvation of ionized groups.

These studies revealed that most of the binding affinity (∼50%) is attributed to the phosphate moiety of the pTyr residue while residues in positions from −2 to +4, relative to the phosphotyrosine, modulate binding specificity.

Although the binding affinity of non-canonical EF-hands is not necessarily weaker than canonical EF-hands, the low binding affinity of EF1 might be attributed to the decrease in entropic contribution.

In previous studies, we established that a family of V-region identical murine IgG1, IgG2a, IgG2b, and IgG3 manifested diverse binding affinity and specificity that were attributed to C region effects on the V region.

The fact that the E57Q/E58Q double mutant displayed an only 4-fold reduction in Dq binding affinity is attributed in great part to the retention of the E120−aminomethylquinolinium interaction and the large number of contacts between QacR and Dq in this preferred binding mode.

We further performed detailed analysis on the amino acid contributions to the binding energies and found that the strong binding affinity for 6F-tricin to CDK9 is attributed to the specific binding orientation of 6F-tricin in the ATP-binding site.

Because WT ToMOH and mutants N202A and Q228A maintain a similar ToMOD-Fl binding affinity, the loss of coupling efficiency in these mutants cannot be attributed to a decreased binding affinity for the regulatory protein.

The binding free energy calculated using the MM/PBSA method suggests that selectivity between AChE1 and AChE2 is mainly attributed to decreased binding affinity for the inhibitor.

An increase in adsorption capacity was attributed to cadmium binding affinity of sulfur atoms due to soft acid base reaction and supported by a − ΔG value [26].