Sentence examples for binding affinity as the from inspiring English sources

These in vitro results are consistent with binding affinity as the Bi-NonGly fusion toxin binds strongest to CD25 on the same LCL13271 cells.

Interestingly, these modifications neither increased nor decreased the relative binding affinity as the novel APLs were found to bind HLA-DR4(B1*0401) with equally high affinity as the WT peptide.

The nodes are drugs and targets, and an edge connects a drug and a target, with the binding affinity as the edge weight.

Truncated proteins lacking this domain show the same binding affinity as the full Sxl protein, but fail to induce female-specific self-splicing of Sxl transcripts [ 21].

Additionally, in preliminary binding experiments on CHO-hMCHR1 cell membranes, FE@SNAP evinced similar binding affinity as the parent compound SNAP-7941 (Kd = 0.18 nM).

Generally, scFvs have the same binding affinity as the monomeric form of the parent antibody, but this is not true in all cases.

These two setups allow us to obtain data on the individual binding affinity as well as the avidity that is inherently linked to the dimeric nature of the ligands.

Biological potencies of the synthesized compounds were assessed in terms of the vitamin D receptor (VDR) binding affinity, as well as the HL-60 cell differentiation-inducing activity.

Thus, we decided to perform a detailed investigation of the pH dependence of the spectroscopic properties of hDDC in its internal and external aldimine forms, of the PLP binding affinity as well as of the steady-state kinetic parameters.

In several recent studies, these effects have successfully been exploited to manipulate protein scaffolds, resulting in improved catalytic activity and altered substrate or ligand binding affinity, as well as enabling the design of novel biocatalysts and biosensors.

Although the charged amino acids in Cluster III of the ligand are distributed in a highly complementary manner, these residues do not contribute to the binding affinity, as was shown by mutagenesis and BIAcore analysis [ 39].