Sentence examples for binding affinity and stability from inspiring English sources
A number of light and heavy chain canonical residue core redesigns were made in a therapeutic antibody (AQC2, anti-VLA1) Fab to explore the consequences to binding affinity and stability.
Furthermore, the adsorption energy, cohesive energy, and adsorption angle demonstrated that the binding affinity and stability of B membrane was remarkably greater than that of A, which indicated that B had better inhibition performance in CO2 corrosion.
We hypothesized that further optimization of LXY1 by modifying individual amino acids could improve its in vivo binding affinity and stability to α3β1 integrin-expressing human cancer xenografts.
Besides, alternation of phosphate group in M6P with phosphonate, carboxylate, or malonate groups leads to improved binding affinity and stability [80 83].
The dimensionless parameter (i.e., ratio of binding affinity) introduced in this work from such experiments is useful in quantitatively depicting such binding affinity, indicating that the binding affinity and stability between AuNPs and catecholamine is approximately 1.5 times stronger than that between amine and AuNPs.
Their multiligand chelation ability enhances their binding affinity and stability.
The three-dimensional structured streptavidin suggests that, without significant modifications, streptavidin would not be able to form a stable, functional molecule in a dimeric or monomeric form, although a dimeric streptavidin with reduced biotin-binding affinity and stability has already been produced.
The single-molecule FRET data highlight that weakened binding affinities and stabilities lead to a dynamic interaction with target DNA, likely though an inability to stably engage in the fully duplexed conformation.
This is supported by low total energy value of docking system, formation of two H-bonds with HCV NS3 protease active site residues, high binding affinity and increased stability in the interaction system.
A fusion which incorporated the C-terminus addition of a positively charged tail (B5-GS3K) improved biosensor sensitivity to CEA while also retaining the sub-nanomolar binding affinity and thermal stability of the unmodified sdAb.
Indeed, TCR binding affinity and pMHC stability adequately account for the observed T cell activation potencies in this system.
